A rare case of isoniazid induced sideroblastic anemia

نویسندگان

چکیده

Sideroblastic anemia is a rare cause of anemia. Most it accounts for the genetic cause, while drug induced still uncommon. Our patient, 20 year old female, known case right frontal tuberculoma on ATT presented with complaints generalized weakness and loss appetite. On evaluation, she was found to have severe bone marrow studies confirmed be sideroblastic revisiting history, noted that not taking pyridoxine supplements as advised along antitubercular drugs. patient one among few documented cases Isoniazid anemia.This needs attention because preventable clinicians need aware about compliance supplementary

منابع مشابه

Severe isoniazid related sideroblastic anemia

Isoniazid induced sideroblastic anemia is a rare event. We report case of a 45 year old Caucasian women with development of severe anaemia 4 month after introduction of Isoniazid as part of Tuberculosis treatment. While haemoglobin fell to 47 g/L and erythrocyte count to 1.5 G/L, reticulocytes were very low (reticulocyte production index of 0.48), but bone marrow aspirate showed an accelerated ...

متن کامل

Sideroblastic anemia.

When first defined 50 years ago, sideroblastic anemia (SA) was already recognized to occur in heterogeneous settings, including as familial or acquired disease. The spectrum of SA has since become considerably expanded with respect to distinct clinical phenotypes as well as discrete causes. The singular feature that typifies all forms of SA and is required for initial diagnosis is the presence ...

متن کامل

Isoniazid induced childhood diabetes: A rare phenomenon

Drugs raise blood glucose concentrations via two broad mechanisms: By reducing insulin biosynthesis or secretion, or by reducing tissue sensitivity to insulin. Until date, there have been very few reported cases of isoniazid induced diabetes. We are presenting a case report of 6-year-old child with isoniazid induced diabetes who was misdiagnosed initially as a case of type 1 diabetes mellitus. ...

متن کامل

Natural history of idiopathic refractory sideroblastic anemia.

We analyzed the natural history of idiopathic refractory sideroblastic anemia (IRSA) in 37 patients studied between 1969 and 1986. Although erythroid abnormalities were prominent in all, 12 patients also showed involvement of the granulocytic and/or megakaryocytic cell lines, and nonrandom chromosomal aberrations were observed in five of 23 patients studied for such defects. Measurements of ery...

متن کامل

Isoniazid Induced Claustrophobia—a Case Report

A case of claustrophobia in a 45-year old male tuberculous in-patient receiving antituberculous drug is reported. The patient presented with the clinical features of claustrophobia after eighteen months of therapy. Isoniazid was, probably, the most likely cause since. The symptoms recurred on reintroduction of INH containing regimens. There was no recurrence of symptoms on resumption of non-Iso...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: International Journal of Research in Medical Sciences

سال: 2023

ISSN: ['2320-6012', '2320-6071']

DOI: https://doi.org/10.18203/2320-6012.ijrms20232448